Half year reported NPATA US$2 billion¹,² Up 13% at constant currency³

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Strong CSL Behring portfolio growth especially Ig

FINANCIAL HIGHLIGHTS4

Revenue $8.05 billion, up 11% at CC3
NPAT $1.90 billion1, up 17%
NPAT $1.94 billion1 at CC3, up 20%
NPATA $2.02 billion1,2 , up 11%
NPATA $2.06 billion1,2 at CC3, up 13%
NPATA1,2 earnings per share $4.182, up 11%

NPATA1,2 earnings per share $4.26 at CC3 up 13%

Interim dividend 5 of US$1.19 per share

Converted to Australian currency, the interim dividend is approximately A$1.81 per share, up 12%

Guidance reaffirmed – FY24 NPATA2,4 anticipated to be in the range of approximately $2.9 billion to $3.0 billion2 at CC3 

MELBOURNE, Australia, Feb. 13, 2024 /PRNewswire/ — CSL Limited ((ASX:CSL, OTC:CSLLY) today announces a reported net profit after tax of $1.90 billion1 for the 6 months ended 31 December 2023, up 20% on a constant currency basis3. Underlying profit (NPATA) was $2.02 billion1,2, up 13% on a constant currency basis to $2.06 billion1,2,3.

Dr. Paul McKenzie, CSL’s Chief Executive Officer and Managing Director said, “Our strong first-half result for the 2024 financial year was driven by CSL Behring’s exceptional performance across its portfolio, especially immunoglobulins.  The plasma initiatives we have implemented are starting to drive gross margin recovery.

“CSL Seqirus achieved solid growth in a challenging season.  Its portfolio of differentiated products outperformed the market.

“For CSL Vifor we are well prepared for the transitioning iron market.”  

PERFORMANCE

CSL Behring

Total revenue was $5,238 million, up 14%3 when compared to the prior comparable period.

Immunoglobulin (Ig) product sales of $2,757 million, increased 23%3 with strong growth recorded across all geographies driven by global plasma supply and patient demand.

PRIVIGEN®  / INTRAGRAM® (Immune Globulin Intravenous (Human), 10% Liquid) sales grew 27%3 as the momentum from the prior year continued in improving product availability and patient diagnosis rates.

HIZENTRA® (Immune Globulin Subcutaneous (Human), 20% Liquid) sales were up 18%3 driven by  patient diagnosis rates.  HIZENTRA® continues to be the clear market leader for subcutaneous immunoglobulin.

Underlying demand for Ig continues to be strong due to significant patient needs in core indications – namely Primary Immune Deficiency, Secondary Immune Deficiency and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).

Albumin sales of $613 million, were up 8%3. 

Sales were strong in emerging markets with solid growth in the US and Europe.  Growth in China was modest, tempered by competitive pressure.

Haemophilia product sales of $662 million increased 8%3.

IDELVION®, CSL Behring’s novel long-acting recombinant factor IX product achieved growth of 7%3  and continues to be the market leader in key markets.

HEMGENIX®, the first and only gene therapy for haemophilia B was successfully launched in the US in FY23 and patient referrals have been accelerating.

The haemophilia A market continued to be competitive resulting in a modest decline in sales for AFSTYLA®, a novel recombinant factor VIII product.

Plasma-derived haemophilia products, however, achieved growth of 8% driven by HUMATE® / HAEMATE®, therapies for the treatment of patients with von Willebrand disease.

Specialty products sales of $976 million, were up 6%3 led predominately by demand for KCENTRA® and HAEGARDA®.  

KCENTRA® (4 factor prothrombin complex concentrate) recorded sales growth of 12%3, as it continues to further penetrate the warfarin reversal market in the US.

HAEGARDA®, our therapy for patients with Hereditary Angioedema, increased 9%, driven by the continued shift from on-demand to prophylaxis treatment and a strong performance in the UK and Europe.

Garadacimab (Anti-FXIIa) for HAE, was filed for regulatory approval in the US and EU.

Plasma Collections

Plasma collections remain strong.  The cost of collections, which includes donor compensation and labour, continued to trend down. 

A new roll out plan for the RIKA plasmapheresis devices was developed.  Deployment across the US fleet is expected over the next 18 months.  In addition, results from an individualised nomogram trial conducted by our supplier have been submitted for regulatory approval.

CSL Seqirus

Total revenue of $1,804 million, was up 2%3 driven by the adjuvanted influenza vaccine FLUAD®, which increased by 14%3.

This growth was achieved against a backdrop of reduced rates of immunisation and highlights the strength of CSL Seqirus’ differentiated product portfolio.

During the period:

Self-amplifying mRNA vaccine for COVID was approved by Japan’s Ministry of Health, Labour and Welfare
aQIVc, a next generation influenza vaccine combining adjuvant technology with cell-based manufacturing, enrolled its last patient in the Phase III clinical study in January 2024.

CSL Vifor

Total revenue was $1,011 million.  The prior comparable period included only 5 months revenue following the acquisition of Vifor Pharma in

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